guilcst Some antivirus or anti-malware software, such as Bit Defender, 360 Browser, or Comodo, may modify or delete Spine's files. This can cause Spine to fail to run completely, or fail at a later point. You'll need to disable such software or safelist Spine's folders. Spine's folders are:
C:\Program Files (x86)\Spine\ (or the folder where you installed Spine)
%UserProfile%\Spine or <user home folder>\Spine
Some antivirus software, such as Comodo, rudely continues to interfere with other programs running on your computer even after disabling it. If safelisting Spine or disabling the antivirus software doesn't work, the only solution may be to uninstall the misbehaving software.
There is not much we can do about this issue, but if you tell us the name of the anti-virus software you are using we may be able to point you to past cases of other users using it.