When you have 'viewport pixel grid' enabled in Spine, it limits the rendering in the viewport to 2048x2048, which is why your artwork gets cut off at that size. This limitation is specific to the viewport rendering within Spine to manage performance and is not a limitation of the exported animation itself. For your Pixi project, the exported animation will not be cut off in the same way as in the Spine viewport, assuming your export settings are configured correctly to handle the desired scale.
For working with pixel art and ensuring it scales correctly without getting cut off, you might want to consider the following workaround: If your animation requires scaling beyond what the viewport can display due to its limitation, focus on the export settings and the setup in Pixi to ensure it can handle larger scales. Spine's export functionality allows for scaling adjustments, and by using the correct scale settings in your Pixi project, you should be able to display your animation at any required size without the limitations you see in the Spine editor viewport.